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1

Impact of the Enfuvirtide Resistance Mutation N43D and the Associated Baseline Polymorphism E137K on Peptide Sensitivity and Six-Helix Bundle Structure †‡

Bai, Xuefang, Wilson, Karen L., Seedorff, Jennifer E., Ahrens, Douglas, Green, Justin, Davison, Donna K., Jin, Lei, Stanfield-Oakley, Sherry A., Mosier, Sarah M., Melby, Thomas E., Cammack, Nick, Wang

Journal:

Year:

2008

Language:

english

File:

PDF, 4.79 MB

english, 2008

2

HCV RNA Helicase Requirement for NS3 Oligomerization is Substrate-dependent: Characterization of RNA Substrates with Different Double Strand Lengths and RNA Binding-dependent Inhibition

Julie Hang, Yanli Yang, Vincent Leveque, Tony Giannetti, George Stepan, Nick Cammack, Klaus Klumpp

Journal:

Antiviral Research

Year:

2008

Language:

english

File:

PDF, 61 KB

english, 2008

3

Phase I/II study of 3TC (lamivudine) in HIV-positive, asymptomatic or mild AIDS-related complex patients

Ingrand, Didier, Weber, Jonathan, Boucher, Charles A.B., Loveday, Clive, Robert, Catherine, Hill, Andrew, Cammack, Nick

Journal:

Year:

1995

File:

PDF, 892 KB

1995

4

RG7128 Alone or in Combination with Pegylated Interferon‐α2a and Ribavirin Prevents Hepatitis C Virus (HCV) Replication and Selection of Resistant Variants in HCV‐Infected Patients

Le Pogam, Sophie, Seshaadri, Amritha, Ewing, Aren, Kang, Hyunsoon, Kosaka, Alan, Yan, Jun‐Mei, Berrey, Michelle, Symonds, Bill, De La Rosa, Abel, Cammack, Nick, Nájera, Isabel

Journal:

The Journal of Infectious Diseases

Year:

2010

Language:

english

File:

PDF, 776 KB

english, 2010

5

HIV fusion and its inhibition in antiretroviral therapy

Dr Michael Greenberg, Nick Cammack, Miklos Salgo, Lynn Smiley

Journal:

Reviews in Medical Virology

Year:

2004

Language:

english

File:

PDF, 258 KB

english, 2004

6

Silibinin (Legalon-SIL) Inhibits HCV Replication In Vitro

Isabel Najera, Vincent Leveque, Matt McCown, Julie Q. Hang, Han Ma, Sonal Rajyaguru, Amy Fung, Yanli Yang, Yang Liu, Simran Kular, Nick Cammack, Peter Ferenci, Klaus Klumpp

Journal:

Antiviral Research

Year:

2009

Language:

english

File:

PDF, 72 KB

english, 2009

7

Characterization of the Intracellular Metabolism of β-d-2′-Deoxy-2′-Fluoro-2′-C-Methyl-Cytidine and the Inhibition of HCV Polymerase NS5B by its 5′-Triphosphate Species

Han Ma, Wen-Rong Jiang, Nicole Robledo, Vincent Leveque, Samir Ali, David Smith, Mohammad Masjedizadeh, Teresa Lara-Jaime, Nick Cammack, Klaus Klumpp, Julian Symons

Journal:

Antiviral Research

Year:

2007

Language:

english

File:

PDF, 68 KB

english, 2007

8

Activity of the isolated HIV RNase H domain and specific inhibition by N-hydroxyimides

Julie Qi Hang, Surendran Rajendran, Yanli Yang, Yu Li, Philippe Wong Kai In, Hilary Overton, Kevin E.B. Parkes, Nick Cammack, Joseph A. Martin, Klaus Klumpp

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 1.97 MB

english, 2004

9

Development of HIV-1 resistance to (−)2′-deoxy-3′-thiacytidine in patients with AIDS or advanced AIDS-related complex

Wainberg, Mark A., Salomon, Horacio, Gu, Zhengxian, Montaner, Julio S.G., Cooley, Timothy P., McCaffrey, Ronald, Ruedy, John, Hirst, Hilary M., Cammack, Nick, Cameron, Janet, Nicholson, Wendy

Journal:

Year:

1995

File:

PDF, 5.21 MB

1995

10

Translation deficiency of the sabin type 3 poliovirus genome: Association with an attenuating mutation C472 → U

Yuri V. Svitkin, Nick Cammack, Philip D. Minor, Jeffrey W. Almond

Journal:

Year:

1990

Language:

english

File:

PDF, 1.60 MB

english, 1990

11

Anti-Human Immunodeficiency Virus and Anti-Hepatitis-B Virus Activities and Toxicities of the Enantiomers of 2'-Deoxy-3'-oxa-4'-thiocytidine and Their 5-Fluoro Analogs in Vitro

Mansour, Tarek S., Jin, Haolun, Wang, Wei, Hooker, Elizabeth U., Ashman, Clare, Cammack, Nick, Salomon, Horacio, Belmonte, Antonietta R., Wainberg, Mark A.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 477 KB

english, 1995

12

Characterization of determinants of genotypic and phenotypic resistance to enfuvirtide in baseline and on-treatment HIV-1 isolates

Sista, Prakash R, Melby, Tom, Davison, Donna, Jin, Lei, Mosier, Sarah, Mink, Mike, Nelson, Emily L, DeMasi, Ralph, Cammack, Nick, Salgo, Miklos P, Matthews, Tom J, Greenberg, Michael L

Journal:

Year:

2004

Language:

english

File:

PDF, 117 KB

english, 2004

13

CD4-BFFI: A novel, bifunctional HIV-1 entry inhibitor with high and broad antiviral potency

Andreas Jekle, Eugene Chow, Erhard Kopetzki, Changhua Ji, Mei Jun Yan, Rosa Nguyen, Surya Sankuratri, Nick Cammack, Gabrielle Heilek

Journal:

Antiviral Research

Year:

2009

Language:

english

File:

PDF, 643 KB

english, 2009

14

Immunosafety Assessment of CD4 MAB-based Bifunctional HIV Entry Inhibitor (CD4-BFFI) using In Vitro Immunoassays

Ford Kirschenbaum, Sandhya Bohini, Harald Kropshofer, Nick Cammack, Surya Sankuratri, Changhua Ji

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 71 KB

english, 2010

15

Development of HIV-1 resistance to (−)2′-deoxy-3′-thiacytidine in patients with AIDS or advanced AIDS-related complex

Wainberg, Mark A., Salomon, Horacio, Gu, Zhengxian, Montaner, Julio S.G., Cooley, Timothy P., McCaffrey, Ronald, Ruedy, John, Hirst, Hilary M., Cammack, Nick, Cameron, Janet, Nicholson, Wendy

Journal:

Year:

1995

File:

PDF, 5.21 MB

1995

16

Inhibition of native hepatitis C virus replicase by nucleotide and non-nucleoside inhibitors

Han Ma, Vincent Leveque, Anniek De Witte, Weixing Li, Than Hendricks, Saundra M. Clausen, Nick Cammack, Klaus Klumpp

Journal:

Year:

2005

Language:

english

File:

PDF, 419 KB

english, 2005

17

Immune reconstitution in HAART-treated children with AIDS

Mike Sharland, Amanda M Watkins, Angus G Dalgleish, Nick Cammack, Mike Westby

Journal:

Year:

1998

Language:

english

File:

PDF, 28 KB

english, 1998

18

Correlation of response to treatment and HIV genotypic changes during Phase III trials with saquinavir and reverse transcriptase inhibitor combination therapy

Race, Esther, Gilbert, Susan M., Sheldon, Jonathan G., Rose, Jane S. L., Moffatt, Alec R., Sitbon, Gisela, Dissanayeke, Shobana R., Cammack, Nick, Duncan, Ian B.

Journal:

Year:

1998

Language:

english

File:

PDF, 193 KB

english, 1998

19

HIV protease genotype and viral sensitivity to HIV protease inhibitors following saquinavir therapy

Craig, Charles, Race, Esther, Sheldon, Jonathan, Whittaker, Lynne, Gilbert, Sue, Moffatt, Alec, Rose, Jane, Dissanayeke, Shobana, Chirn, Gung-Wei, Duncan, Ian B., Cammack, Nick

Journal:

Year:

1998

Language:

english

File:

PDF, 181 KB

english, 1998

20

The potential for HIV fusion inhibition

Journal:

Current Opinion in Infectious Diseases

Year:

2001

Language:

english

File:

PDF, 73 KB

english, 2001

21

Structure-Activity Relationships Among a New Class of Antiviral Heterosubstituted 2',3'-Dideoxynucleoside Analogues

Mansour, Tarek, Jin, Haolun, Wang, Wei, Dixit, Dilip, Evans, Colleen, Tse, H. L. Allan, Belleau, Bernard, Gillard, John, Hooker, Elizabeth, Ashman, Claire, Cammack, Nick, Salomon, Horacio, Belmonte, A

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

1995

Language:

english

File:

PDF, 387 KB

english, 1995

22

Substrate-dependent inhibition or stimulation of HIV RNase H activity by non-nucleoside reverse transcriptase inhibitors (NNRTIs)

Julie Q. Hang, Yu Li, Yanli Yang, Nick Cammack, Tara Mirzadegan, Klaus Klumpp

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 665 KB

english, 2007

23

Different Incorporation Efficiencies for Nucleotide Analogs During HCV Polymerase RNA Synthesis Initiation and Elongation Phases

Han Ma, Nicole Inocencio, Vincent Leveque, Genadiy Kalayanov, David Smith, Nick Cammack, Nils Gunnar Johansson, Klaus Klumpp

Journal:

Antiviral Research

Year:

2008

Language:

english

File:

PDF, 74 KB

english, 2008

24

In vitro selected Con1 subgenomic replicons resistant to 2′-C-Methyl-Cytidine or to R1479 show lack of cross resistance

Sophie Le Pogam, Wen-Rong Jiang, Vincent Leveque, Sonal Rajyaguru, Han Ma, Hyunsoon Kang, Sharon Jiang, Margaret Singer, Samir Ali, Klaus Klumpp, Dave Smith, Julian Symons, Nick Cammack, Isabel Nájera

Journal:

Year:

2006

Language:

english

File:

PDF, 275 KB

english, 2006

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